Ozgene and Gen-H partner on OzBIG humanizations

Antibiotic-free Fermentation

We are excited to announce our new technology for antibiotic-free bacterial fermentation

Recent Gen-H Publications

Here is a list of our recent publications. Don’t hesitate to reach out to us if you have any questions.

Gen-H assists to fight SARS Cov2

Gen-H assists the Spanish National Cancer Research Centre

Genetic Engineering
in Heidelberg

Quality Made in Germany

Mouse model generation

Quality Made in Germany

E. coli strain engineering

Quality Made in Germany

GEN-H – Genetic Engineering Heidelberg GmbH

After 17 years and more than 800 successful DNA engineering projects, the Service Unit of Gene Bridges GmbH was transformed into an independent company by a management buy-out with the effective date January 1st 2020.

The company continues to operate from the Technology Park in Heidelberg, Germany,  close to the well-known wine area, “Bergstrasse, Odenwald”. The Technology Park provides an excellent network for innovation.

Gen-H’s team of scientists has extensive experience in Genetic Engineering, gained through daily application of Red/ET recombination (also known as Recombineering). This technology, originally developed at the EMBL in Heidelberg, allows precise, scarless modification of DNA. Gen-H uses this technology to generate complex targeting constructs for animal models, as well as for custom modification of the E. coli chromosome, e.g. for pathway engineering.

These are the things that make us different


Experienced scientists

Your challenging projects are our daily business

More than 1000 projects

Satisfied clients from academia, biotech and pharma companies all over the world


Direct communication

One of our specialists will assist and advise, starting from the initial project strategy to the final construct

Our Services


Recombineering (Red/ET recombination) has become the method of choice to engineer large replicons, such as bacterial artificial chromosomes (BACs). Since recombineering can be performed at any position in the DNA, the technology has opened up an unlimited number of possibilities for the assembly of large and highly complex genetic constructs. 


Escherichia coli is an important producer organism in industrial biotechnology and represents the best studied prokaryotic model organism. Genetic modified strains are used to express industrially important proteins and enzymes, as well as to enzymatically produce fine chemicals. Metabolic engineering is becoming increasingly important to optimize strains to meet commercial objectives…

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    How to find us

    Gen-H Genetic Engineering Heidelberg GmbH
    Im Neuenheimer Feld 584
    69120 Heidelberg