Ozgene and Gen-H partner on OzBIG humanizations

Antibiotic-free Fermentation

We are excited to announce our new technology for antibiotic-free bacterial fermentation

Recent Gen-H Publications

Here is a list of our recent publications. Don’t hesitate to reach out to us if you have any questions.

Gen-H assists to fight SARS Cov2

Gen-H assists the Spanish National Cancer Research Centre

Genetic Engineering
in Heidelberg

Quality Made in Germany

Mouse model generation

Quality Made in Germany

E. coli strain engineering

Quality Made in Germany

GEN-H – Genetic Engineering Heidelberg GmbH

After 17 years and more than 800 successful DNA engineering projects, the Service Unit of Gene Bridges GmbH was transformed into an independent company by a management buy-out with the effective date January 1st 2020.

The company continues to operate from the Technology Park in Heidelberg, Germany, which provides an excellent network for innovation and high-tech in the area of the well-known wine area “Bergstrasse, Odenwald”.

Gen-H’s team of scientists has a vast experience in Genetic Engineering due to its daily application of Red/ET recombination (“Recombineering”). This technology originally developed at the EMBL in Heidelberg allows well-defined and precise modification of DNA to create tailor-made constructs for the generation of animal models, as well as for the modification of the E. coli chromosome, e.g. for pathway engineering.

These are the things that make us different


Experienced scientists

Your challenging projects are our daily business

More than 1000 projects

Satisfied clients from academia, biotech and pharma companies all over the world


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One of our specialists will assist and advise you from the project strategy to the final construct

Our Services


Recombineering (Red/ET recombination) has become the method of choice to engineer large replicons, such as targeting constructs (large high-copy plasmids, low-copy plasmids) or bacterial artificial chromosomes (BACs). Since recombineering can be performed at any position in the DNA the technology has opened up an unlimited number of possibilities for even complex genetic modifications.


Escherichia coli is one important producer organism in industrial biotechnology and represents the best studied and understood prokaryotic model organism in microbiology. Genetic modified strains are used constantly to express industrial important proteins, enzymes, or fine chemicals. Metabolic engineering has become more and more attractive to optimize strains to meet commercial objectives…

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    How to find us

    Gen-H Genetic Engineering Heidelberg GmbH
    Im Neuenheimer Feld 584
    69120 Heidelberg