News

Publication alert!

Jan 11, 2024

Are you looking for bacterial antibiotic-free plasmid fermentation solutions?

We are excited to announce our method has been published in Microbial Cell Factories. We created a simple and flexible plasmid maintenance system by creating an E. coli strain with an essential gene under the control of an inducible promoter; the absence of the inducer creates strong selection pressure for a complementing plasmid. Once engineered, the strain can be propagated without plasmid (via inducer supplementation) and easily transformed with any complementing plasmid. We show this strategy works in a variety of E. coli strains and yields tight plasmid selection, without using any antibiotics or antibiotic resistance genes.

Take a look at the data yourself: https://bit.ly/3SdxMDa

 

Let’s stop the reliance on antibiotics in microbial fermentation, so we can safeguard their effectivity for use in medicine.  

Genetic Engineering Made in Germany

Get everything to know about our services

How to find us

Gen-H Genetic Engineering Heidelberg GmbH
Im Neuenheimer Feld 584
69120 Heidelberg